Differences between Advil and Motrin

From diff.wiki

Advil vs. Motrin[edit]

Advil and Motrin are two of the most common brand names for ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID).[1][2] Both medications are used to relieve pain, reduce fever, and decrease inflammation.[3] While they share the same active ingredient and are largely interchangeable for consumers, there are minor differences in their branding, ownership, and product lines.[4]

Advil was first introduced in the United States in 1984 and is currently owned by Haleon.[5] Motrin, on the other hand, was first marketed in the U.S. in 1974 as a prescription drug and is now produced by Johnson & Johnson. Both became available for over-the-counter use in the mid-1980s.[5]

The standard over-the-counter dose for both Advil and Motrin is 200 mg of ibuprofen per tablet.[1] Higher strengths are available by prescription.[1] Both brands offer a variety of formulations, including tablets, capsules, and liquid gels. They also have product lines that combine ibuprofen with other active ingredients to target specific symptoms, such as Advil Cold & Sinus, which includes a decongestant, and Motrin PM, which contains a sleep aid.[4]

Since Advil and Motrin contain the same active ingredient, they work in the same way and have the same potential side effects.[2] Common side effects can include stomach pain, heartburn, and nausea. More serious, though less common, side effects associated with NSAIDs like ibuprofen include an increased risk of stomach ulcers, kidney problems, and cardiovascular events, particularly with long-term use or at higher doses.[2] It is important not to take both medications at the same time, as this increases the risk of side effects.[1]

Comparison Table[edit]

Category Advil Motrin
Active Ingredient Ibuprofen Ibuprofen
Drug Class Nonsteroidal anti-inflammatory drug (NSAID) Nonsteroidal anti-inflammatory drug (NSAID)
Common Uses Pain relief, fever reduction, inflammation reduction Pain relief, fever reduction, inflammation reduction
Manufacturer Haleon Johnson & Johnson
Year Introduced (U.S.) 1984 (over-the-counter)[5] 1974 (prescription)
Standard OTC Dose 200 mg[1] 200 mg[1]
Product Variations Includes formulations for cold and sinus, and pain with a sleep aid.[5][4] Includes formulations for children and a PM version with a sleep aid.[4]
Venn diagram for Differences between Advil and Motrin
Venn diagram comparing Differences between Advil and Motrin


Formulations and Dosage[edit]

Both Advil and Motrin are available in a variety of forms, including tablets, caplets, and liquid-filled capsules. The standard adult dosage for over-the-counter use is one to two 200 mg tablets every four to six hours as needed for pain or fever. The maximum recommended daily dose without a doctor's supervision is 1200 mg. For inflammatory conditions like arthritis, a doctor may prescribe higher doses, up to 3200 mg per day.

Both brands offer specialized products for children, with dosages based on the child's weight and age. It is not recommended to give ibuprofen to children under six months of age without consulting a healthcare provider.

Side Effects and Warnings[edit]

As both medications contain ibuprofen, they share the same potential side effects. The most common side effects are gastrointestinal, including nausea, heartburn, and indigestion.[1] Taking the medication with food or milk can help to reduce stomach irritation.

More severe potential side effects of ibuprofen include an increased risk of gastrointestinal bleeding, ulcers, and perforation, especially in those who take it for an extended period, are older, or consume alcohol.[2] Ibuprofen can also increase the risk of heart attack and stroke, and it may cause high blood pressure and kidney damage. Individuals with a history of heart, kidney, or stomach problems should consult a doctor before using ibuprofen. It is also important not to take ibuprofen with other NSAIDs, such as aspirin or naproxen, to avoid increasing the risk of adverse effects.[2]


References[edit]

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 "verywellhealth.com". Retrieved January 21, 2026.
  2. 2.0 2.1 2.2 2.3 2.4 "drugs.com". Retrieved January 21, 2026.
  3. "goodrx.com". Retrieved January 21, 2026.
  4. 4.0 4.1 4.2 4.3 "oreateai.com". Retrieved January 21, 2026.
  5. 5.0 5.1 5.2 5.3 "wikipedia.org". Retrieved January 21, 2026.